Syphilis Test and Treatment in Singapore

Medically Reviewed By: Dr Jana Lim, Board-Accredited Family Physician

Board-Accredited Family Physician | MBChB, MMed (FM)

MBChB, MMed (FM) | Last updated: 12 Oct 2026

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What Is Syphilis?

Syphilis is a curable sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. It can lead to serious health complications if it is not treated.

Syphilis develops in stages and often starts with mild or easily missed symptoms, so early diagnosis and treatment are important to prevent long-term damage.

In Singapore, syphilis was among the 3 most commonly reported STIs in 2018.

Syphilis Symptoms and Stages

Syphilis develops in progressive stages, and each phase presents different signs that may vary in severity or visibility. Some individuals may not notice symptoms, allowing the infection to persist unnoticed.

1. Primary Stage

The earliest sign of syphilis is typically a small, round, and painless sore known as a chancre. It usually appears between 10 days and 3 months after exposure, with an average incubation period of about 21 days.

The sore develops at the site where the bacteria entered the body, such as the genitals, rectum, or mouth. Although a chancre may heal on its own within 3 to 6 weeks, this does not indicate that the infection has been resolved.

2. Secondary Stage

At this point, the infection spreads throughout the body, often causing a widespread rash that can develop on the palms, soles, or other areas. These rashes are generally not itchy. Moist, raised lesions may appear in areas like the mouth, genitals, or throat.

Other symptoms may include fever, swollen lymph nodes, muscle aches, fatigue, and patchy hair loss. These symptoms may disappear without treatment, but the infection remains active.

3. Latent Stage

During the latent phase, no visible symptoms are present, but the bacteria continue to reside in the body. This stage can last for years and may go unnoticed without testing. If untreated, the condition can progress to a more dangerous phase.

4. Late Stage (Tertiary Stage)

This stage may develop years or even decades after the initial infection if syphilis remains untreated. It is marked by serious complications, which can include:

• Damage to vital organs such as the brain, nerves, eyes, heart, and others
• Neurological problems, including memory impairment and difficulty with coordination
• Cardiovascular damage, such as inflammation or weakening of blood vessels

How Is Syphilis Tested and Diagnosed?

Testing for syphilis typically involves a blood test that detects antibodies (proteins produced by the immune system to fight infection) in response to Treponema pallidum.

If visible signs such as sores are present, a swab or physical examination may also be performed.

How Long Does a Syphilis Test Take?

At our clinics, sample collection for syphilis testing generally takes less than 30 minutes if performed during off-peak hours. Contact us to find out the best time to schedule your appointment to reduce waiting.

Results are typically ready within 2 to 4 working days. We will notify you once they are ready for review.

Is Syphilis Curable?

Yes, syphilis can be fully cured, especially when identified and treated in its early stages. While treatment can eliminate the infection and prevent further complications, it may not reverse damage that has already occurred during the later stages of the disease.

What Is the Treatment for Syphilis?

Treatment for syphilis typically involves antibiotics, with the dosage and schedule depending on the stage of infection and whether complications are present. It is important to complete the full course of prescribed treatment and refrain from sexual activity until follow-up blood tests confirm that the infection has been fully cleared.

How Much Does Syphilis Testing and Treatment Cost?

At Singapore Women's Clinic, we offer confidential and prompt testing and treatment for syphilis and other STIs. Our pricing is as follows:

Test / Treatment	Price*
Consultation	From $49.05
Syphilis Antibody Blood Test (Syphilis TP Ab)	$21.80
STD Screening Packages
Safe Screen 1 (3 tests) – Blood Test HIV, Syphilis, Hepatitis B HIV, Syphilis, Hepatitis B	$58
Safe Screen 2 (4 tests) – Blood Test HIV, Syphilis, Hepatitis B, Hepatitis C HIV, Syphilis, Hepatitis B, Hepatitis C	$98
Safe Screen 3 (6 tests) – Blood Test HIV, Syphilis, Hepatitis B, Hepatitis C, Herpes Simplex Virus 1 and 2 HIV, Syphilis, Hepatitis B, Hepatitis C, Herpes Simplex Virus 1 and 2	$148
Essential (8 tests) – Blood + Swab Test HIV, Syphilis, Hepatitis B, Hepatitis C, Herpes Simplex Virus 1 and 2, Chlamydia PCR, Gonorrhoea PCR HIV, Syphilis, Hepatitis B, Hepatitis C, Herpes Simplex Virus 1 and 2, Chlamydia PCR, Gonorrhoea PCR	$288
Complete Female STD Screen (15 tests) – Blood + Swab Test HIV, Syphilis, Hepatitis B, Hepatitis C, Herpes Simplex Virus 1 and 2, Chlamydia, Gonorrhoea, Mycoplasma genitalium, Mycoplasma hominis, Trichomonas, Ureaplasma parvum, Ureaplasma urealyticum, Monilia / Candida, Gardnerella Vaginosis HIV, Syphilis, Hepatitis B, Hepatitis C, Herpes Simplex Virus 1 and 2, Chlamydia, Gonorrhoea, Mycoplasma genitalium, Mycoplasma hominis, Trichomonas, Ureaplasma parvum, Ureaplasma urealyticum, Monilia / Candida, Gardnerella Vaginosis	$478
Genital Ulcer PCR Testing (7 tests) – Swab Test Herpes Simplex Virus 1 and 2, Haemophilus Ducreyi (Chancroid), Cytomegalovirus, Lymphogranuloma Venereum, Treponema Pallidum (Syphilis), Varicella Zoster Virus Herpes Simplex Virus 1 and 2, Haemophilus Ducreyi (Chancroid), Cytomegalovirus, Lymphogranuloma Venereum, Treponema Pallidum (Syphilis), Varicella Zoster Virus	$318
Enhanced Genital Ulcer Testing (18 tests) – Blood + Swab Test Blood: HIV, Syphilis, Hepatitis B, Hepatitis C Ulcer PCR Swab: Herpes Simplex Virus 1 and 2, Haemophilus Ducreyi (Chancroid), Cytomegalovirus, Lymphogranuloma Venereum, Treponema Pallidum (Syphilis), Varicella Zoster Virus Genital Swab: Chlamydia, Gonorrhoea, Mycoplasma genitalium, Mycoplasma hominis, Trichomonas, Ureaplasma parvum, Ureaplasma urealyticum Blood: HIV, Syphilis, Hepatitis B, Hepatitis C Ulcer PCR Swab: Herpes Simplex Virus 1 and 2, Haemophilus Ducreyi (Chancroid), Cytomegalovirus, Lymphogranuloma Venereum, Treponema Pallidum (Syphilis), Varicella Zoster Virus Genital Swab: Chlamydia, Gonorrhoea, Mycoplasma genitalium, Mycoplasma hominis, Trichomonas, Ureaplasma parvum, Ureaplasma urealyticum	$538
Treatment
Antibiotics Injection (1 Dose)	$81.75
Antibiotics Injection (3 Doses)	$212.55

*All prices are NETT and inclusive of GST.

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