Medically Reviewed By: Dr Jana Lim | MBChB, MMed | Board-Accredited Family Physician
MBChB, MMed | Board-Accredited Family Physician
Malaria prophylaxis involves taking prescribed medication to protect against malaria infection when travelling to
countries where the disease is prevalent. These medicines act as preventive treatment to stop
malaria parasites from multiplying within the body after an infected mosquito bite.
Malaria is caused by Plasmodium parasites,
specifically P. falciparum, P. vivax, P. malariae, P. ovale, and
P. knowlesi, and is spread through bites from infected female Anopheles
mosquitoes. Once in the bloodstream, the parasites attack red blood cells and can cause serious
illness if not prevented or treated early.
Using prophylaxis reduces not only the traveller’s individual risk but also helps prevent the
importation of malaria into malaria-free countries such as Singapore. Local transmission has been
kept low through vigilant public health surveillance and mosquito control programmes. Reported
imported malaria cases have remained under 40 each year since
2018, illustrating the importance of preventive care, including medication before and after
travel.
Malaria often begins with symptoms that resemble a viral infection, but it can rapidly progress to severe disease if untreated. The illness usually develops about one to several weeks after a bite from an infected mosquito.
Typical symptoms include:
If medical care is delayed, malaria can cause complications such as severe anaemia, breathing difficulties, seizures, organ failure, or in extreme cases, death. Pregnant women, young children, and individuals with compromised immunity are particularly susceptible to severe malaria.
Anti-malarial medicines work by interrupting
the parasite’s life cycle before it can establish infection in the body. Some
act on the liver stage where parasites first develop, while others target parasites circulating in
the blood. By blocking these stages, the medication helps prevent the disease from progressing even
after a mosquito bite.
Commonly prescribed preventive medications include atovaquone-proguanil,
doxycycline, mefloquine, and chloroquine. As these are prescription-only
medicines, you will need to consult a doctor for a medical assessment before obtaining them.
The choice of prophylaxis depends on several factors such as travel destination, regional
resistance patterns, duration of stay, existing medical conditions, and possible drug
interactions. Your doctor can advise on the most appropriate regimen, discuss possible
side effects, and recommend additional preventive steps such as using insect repellent and wearing
protective clothing.
Malaria prophylaxis should begin before entering an area where malaria is prevalent and
continue throughout the trip as well as for a period after returning home. This schedule ensures
that any parasites introduced during travel are effectively cleared from the body.
The timing for starting and stopping
medication varies according to the specific drug prescribed. Some regimens,
such as mefloquine, should begin one to two weeks before departure and continue for several weeks
after returning. Others, such as atovaquone-proguanil, can be started one or two days before travel
and stopped about a week after leaving the area.
It is essential to follow the recommended schedule precisely, as missing doses or stopping early may
leave you vulnerable to infection. Consult your doctor well in advance of your trip to ensure you
begin the medication at the appropriate time.
Most people tolerate malaria prophylaxis without problems, though some may experience mild, short-lived side effects. Common symptoms can include:
These reactions usually ease as your body adjusts to the medicine. To reduce discomfort, take the medication
with food or at the same time each day as advised by your doctor.
If you experience severe or persistent symptoms such as intense stomach pain, mood changes, vision problems,
irregular heartbeat, or allergic reactions like rash and swelling, seek medical advice promptly. Your doctor
may switch you to an alternative anti-malarial that is better suited to your needs.
At Singapore Women's Clinic, we offer anti-malarial medications with the following prices:
| Medication | Price* |
|---|---|
| Consultation | From $49.05 |
|
Malarone (Atovaquone-Proguanil)
Typical Dosage: 2 days + duration of travel + 7 days after returning (1 tab per day) |
$15.59 per tab |
|
Doxycycline
Typical Dosage: 2 days + duration of travel + 28 days after returning (1 tab per day) |
$1.09 per tab |
*All prices are NETT and inclusive of GST.
In addition to malaria prophylaxis, we provide a wide selection of travel-related vaccinations and a travel medical kit designed to keep you well protected and ready for any health needs during your journey.
Address
1 Orchard Boulevard, #05-09, Camden Medical Centre, S248649
Parking
Camden Medical Centre Carpark
MRT Access
Orchard Boulevard (TE13): 2-minute walk
Orchard (NS22): 8-minute walk
Opening Hours
Mon - Fri: 8:30 AM – 5:30 PM
Sat: 8:30 AM – 12:30 PM
Sun & PH: Closed
Address
72 Anson Rd, #01-02, Anson House, S079911
Parking
Anson House Carpark
MRT Access
Tanjong Pagar (EW15): 4-minute walk
Opening Hours
Mon - Fri: 8:30 AM – 12:30 PM, 1:30 PM – 5:30 PM
Sat: 8:30 AM – 12:30 PM
Sun & PH: Closed
Address
21 Jurong Gateway Rd, #02-08, CPF Jurong Service Centre, S608546
Parking
Blk 132 Jurong Gateway Rd (Multi-storey Car Park)
MRT Access
Jurong East (EW24 / NS1): Exit D (5-min walk)
Opening Hours
Mon - Fri: 8:30 AM – 12:30 PM, 1:30 PM – 5:30 PM
Sat: 8:30 AM – 12:30 PM
Sun & PH: Closed